5D model-based treatment personalization for right-time adaptive proton therapy

KU Leuven is currently by far the largest university in Belgium in terms of research funding and expenditure (EUR 740 million in 2023), and is a charter member of League of European Research Universities (LERU). The proton center is fully integrated within the existing academic hospital. The center encompasses two vaults, with their own accelerator: one for the treatment of patients and one dedicated vault for research purposes. A Proteus®ONE system capable of pencil beam scanning is installed with the full scope of imaging modalities (kV-kV, CBCT), including an in-room dual energy CT on-rails.

Project

Applications should be exclusively submitted through the consortium webpage RAPTORplus aims at adapting proton therapy treatment with multi-modality image information acquired at various time scales. Daily anatomical changes would be characterized by on-board X-ray based imaging systems (or eventually MRI), while longer term biological modifications...