Postdoc Nitika Taneja

An opportunity to study the molecular mechanisms of underlying DNA replication at one of the largest University Medical Centres in the country.

Job description

DNA replication represents a crucial, but potentially dangerous process that cells must complete to undergo cellular division. A failure to properly maintain the integrity of replicating chromosomes inevitably leads to genome instability, which is an early event in tumorigenesis. The candidate will be part of a young research team studying molecular and the structural mechanisms underlying DNA replication stress-its role in tumorigenesis and chemoresistance. To study the molecular effects of replication stress and the factors associated with it, molecular cloning, in vitro and in vivo CRISPR/Cas9 genome editing, modern sequencing and proteomics technologies and mouse transplantations in combination with structural technologies like Electron Microscopy and single molecule imaging...