Protein Structure Analyst

Job Description:

- We are seeking a highly skilled and motivated Structural Biologist to join our drug

discovery programs. The ideal candidate will bring deep expertise in

macromolecular structure determination and modeling, with a focus on elucidating

protein structures, analyzing ligand binding, and driving rational drug design in

collaboration with computational and medicinal chemistry teams.

Key Responsibilities:

- Analyze protein-ligand interactions to inform medicinal chemistry and lead

optimization efforts.

- Conduct molecular dynamics (MD) simulations and free energy calculations to

evaluate complex stability and binding energetics.

- Apply structural insights to guide hit-to-lead and lead optimization strategies.

- (Preferred) Utilize machine learning models to support binding site prediction or

compound prioritization.

Required Skills & Experience: