Structural Biologist

Job Description:

• We are seeking a highly skilled and motivated Structural Biologist to join our drug

discovery programs. The ideal candidate will bring deep expertise in

macromolecular structure determination and modeling, with a focus on elucidating

protein structures, analyzing ligand binding, and driving rational drug design in

collaboration with computational and medicinal chemistry teams.

Key Responsibilities:

• Analyze protein-ligand interactions to inform medicinal chemistry and lead

optimization efforts.

• Conduct molecular dynamics (MD) simulations and free energy calculations to

evaluate complex stability and binding energetics.

• Apply structural insights to guide hit-to-lead and lead optimization strategies.

• (Preferred) Utilize machine learning models to support binding site prediction or

compound prioritization.

Required Skills & Experience:

• Strong e...